0319/2020 - Risco de iniciação ao tabagismo com o uso de cigarros eletrônicos: revisão sistemática e meta-análise Risk of smoking initiationwiththe use ofelectroniccigarettes: systematic review and meta-analysis
Objetivo: Avaliar a associação entre uso de cigarros eletrônicos e iniciação ao tabagismo, por meio de uma revisão sistemática com meta-análise de estudos longitudinais.Métodos:Busca bibliográfica foi realizada nas bases Medline, Embase, Lilacs e PsycInfo. As etapas de seleção de referências, extração dos dados e avaliação do risco de viés dos estudos foi realizada em dupla, de forma independente e as divergências discutidas com um terceiro pesquisador para obtenção de consenso. Meta-análise foi realizada por meio do modelo Mantel-Haenszel de efeitosaleatórios.Resultados: Dentre os 25 estudos incluídos, 22 avaliaram o desfecho de experimentação de cigarro convencional e nove avaliaram o desfecho de tabagismo atual (nos últimos 30 dias). A meta-análise demonstrou que o uso de cigarro eletrônico aumentou em quase três vezes e meia o risco de experimentação de cigarro convencional (RR=3,42; IC95% 2,81 – 4,15) e em mais de quatro vezes o risco de tabagismo atual (RR=4,32; IC95% 3,13 – 5,94). Conclusões: O risco de iniciação ao tabagismo é significativamente maior entre usuários de cigarro eletrônico. A liberação da comercialização desses dispositivos pode representar uma ameaça para as políticas de saúde pública no Brasil.
Palavras-chave:
Sistemas Eletrônicos de Liberação de Nicotina; Tabagismo; Prevenção do Hábito de Fumar; Revisão Sistemática, Meta-análise.
Abstract:
Objective: To evaluate the association between the use of electronic cigarettes and smoking initiation, through a systematic review with meta-analysis of longitudinal studies. Methods: Bibliographic search was performed on Medline, Embase, Lilacs and PsycInfo databases. Reference ion, data extraction and risk of bias assessment of the studies were independently carried out in pairs, and the disagreements were discussed with a third researcher to reach consensus. A meta-analysis was performed using the Mantel-Haenszel model with a random effect. Results: Among the 25 included studies, 22 evaluated the outcome of conventional cigarettes experimentation and nine assessed the outcome of current smoking (in the last 30 days). The meta-analysis showed that the use of electronic cigarettes increased the risk of conventional cigarettes experimentation by almost three and a half times (RR = 3.42; 95% CI 2.81 - 4.15), and by more than four times the risk of current smoking (RR = 4.32; 95% CI 3.13 - 5.94). Conclusions: The risk of smoking initiation is significantly higher among electronic cigarettes users. The marketing authorizationof such devices may represent a threat to the public health policies in Brazil.
Risk of smoking initiationwiththe use ofelectroniccigarettes: systematic review and meta-analysis
Resumo (abstract):
Objective: To evaluate the association between the use of electronic cigarettes and smoking initiation, through a systematic review with meta-analysis of longitudinal studies. Methods: Bibliographic search was performed on Medline, Embase, Lilacs and PsycInfo databases. Reference ion, data extraction and risk of bias assessment of the studies were independently carried out in pairs, and the disagreements were discussed with a third researcher to reach consensus. A meta-analysis was performed using the Mantel-Haenszel model with a random effect. Results: Among the 25 included studies, 22 evaluated the outcome of conventional cigarettes experimentation and nine assessed the outcome of current smoking (in the last 30 days). The meta-analysis showed that the use of electronic cigarettes increased the risk of conventional cigarettes experimentation by almost three and a half times (RR = 3.42; 95% CI 2.81 - 4.15), and by more than four times the risk of current smoking (RR = 4.32; 95% CI 3.13 - 5.94). Conclusions: The risk of smoking initiation is significantly higher among electronic cigarettes users. The marketing authorizationof such devices may represent a threat to the public health policies in Brazil.
Barufaldi, L.A, Guerra, R.L, Albuquerque, R.C.R, Nascimento, A, Chança, R.D, Souza, M.C., Almeida, L.M. Risco de iniciação ao tabagismo com o uso de cigarros eletrônicos: revisão sistemática e meta-análise. Cien Saude Colet [periódico na internet] (2020/out). [Citado em 24/12/2024].
Está disponível em: http://cienciaesaudecoletiva.com.br/artigos/risco-de-iniciacao-ao-tabagismo-com-o-uso-de-cigarros-eletronicos-revisao-sistematica-e-metaanalise/17801?id=17801
