1074/2012 - Deficiência de micronutrientes e crescimento linear: revisão sistemática de estudos observacionais Micronutrients deficiencies and linear growth: a systematic review
• Ana Carolina Dantas Rocha - ROCHA, ACD - Universidade Estadual da Paraíba (mestranda) - <aninhacdr@hotmail.com>
• Márcia Cristina Sales - Sales, M.C. - Natal, RN - Universidade Estadual da Paraíba (mestranda) - <cristina.salles@yahoo.com.br>
Área Temática:
Alimentação, Nutrição e Saúde
Resumo:
Objetivo: Avaliar a associação das deficiências de ferro, vitamina A e zinco com o déficit de crescimento linear. Métodos: Revisão sistemática nas bases de dados eletrônicas PubMed, LILACS e SciELO. Foram selecionados artigos publicados entre janeiro de 1995 e março de 2010, considerando os descritores: (growth OR nutritional status) AND (child, preschool OR infant) AND (zinc AND iron AND vitamin A) OR (zinc AND iron) OR (zinc AND vitamin A) OR (iron AND vitamin A). Resultados: Foram revisados 14 estudos de delineamento observacional. Dos estudos tipo coorte (dois), um indicou associação estatística entre o estado nutricional de ferro e o déficit de estatura; o outro apontou associação estatística entre as concentrações de ferritina sérica e o ganho de estatura. Dez estudos transversais investigaram a associação estatística entre as deficiências de micronutrientes e o déficit de estatura, resultando três deles na associação para o ferro, dois para a vitamina A e nenhum para o zinco. Conclusões: O esclarecimento sobre a associação entre o déficit de estatura e as deficiências de ferro, vitamina A e zinco dificulta-se por fatores de caráter biológico e relacionados à magnitude das deficiências, o que sugere a importância da padronização metodológica dos estudos. Os resultados permitem a composição de um panorama preliminar da associação entre anemia e déficit de estatura.
Palavras-chave:
crescimento linear
estatura
déficit de estatura
ferro
vitamina A
zinco
Abstract:
Objective: To evaluate the association of iron, vitamin A and zinc deficiencies on linear growth retardation. Methods: A systematic review of electronic databases in PubMed, LILACS and SciELO. There were selected scientific papers published between January 1995 and March 2010, considering the keywords: (growth OR nutritional status) AND (child, preschool OR infant) AND (zinc AND iron AND vitamin A) OR (zinc AND iron) OR (zinc AND vitamin A) OR (iron AND vitamin A). Results: It was reviewed 14 observational design studies. From the cohort studies (two), one indicated a statistical association between iron status and stunting; and the other pointed out the statistical association between serum ferritin concentrations and the gain in height. Ten cross-sectional studies investigated the statistical association between micronutrient deficiencies and stunting, resulting three of them in association for iron, two for vitamin A and none for zinc. Conclusions: The clarification of the association between stunting and iron, vitamin A and zinc deficiencies involves difficulty by biological factors and related to the magnitude of these deficiencies, suggesting the importance of standardizing methodological of the studies. The findings show a preliminary overview about association between anemia and stunting.
Micronutrients deficiencies and linear growth: a systematic review
Resumo (abstract):
Objective: To evaluate the association of iron, vitamin A and zinc deficiencies on linear growth retardation. Methods: A systematic review of electronic databases in PubMed, LILACS and SciELO. There were selected scientific papers published between January 1995 and March 2010, considering the keywords: (growth OR nutritional status) AND (child, preschool OR infant) AND (zinc AND iron AND vitamin A) OR (zinc AND iron) OR (zinc AND vitamin A) OR (iron AND vitamin A). Results: It was reviewed 14 observational design studies. From the cohort studies (two), one indicated a statistical association between iron status and stunting; and the other pointed out the statistical association between serum ferritin concentrations and the gain in height. Ten cross-sectional studies investigated the statistical association between micronutrient deficiencies and stunting, resulting three of them in association for iron, two for vitamin A and none for zinc. Conclusions: The clarification of the association between stunting and iron, vitamin A and zinc deficiencies involves difficulty by biological factors and related to the magnitude of these deficiencies, suggesting the importance of standardizing methodological of the studies. The findings show a preliminary overview about association between anemia and stunting.
