0419/2017 - Fatores associados à adesão à Terapia Antirretroviral em adultos: Revisão integrativa de literatura. Factors associated with antiretroviral therapy adherence in adults: Integrative review.
A aids é uma manifestação clínica avançada da infecção pelo HIV. Gera imunodeficiência grave e inúmeras infecções associadas, podendo levar à morte. A disponibilidade da Terapia Antirretroviral (TARV) diminuiu a morbi-mortalidade do HIV/aids, mas seus benefícios dependem da adesão ao tratamento. Esta revisão integrativa da literatura seguiu a estratégia PICO para identificar os fatores associados à adesão à TARV em adultos. Foram consultadas as bases MEDLINE, SciELO, LILACS e PePSIC e incluídos artigos publicados entre janeiro de 2010 e dezembro de 2016. Foram analisados 125 artigos, quanto as características dos estudos, medidas de adesão e fatores associados. Os resultados mostraram grande variação na definição da adesão e no uso das medidas para seu monitoramento, além de inúmeros fatores associados à adesão. Esses foram agrupados em categorias, sendo elas: 1.variáveis individuais; 2. características do tratamento; 3.características da infecção pelo HIV/aids; 4. relação com o serviço de saúde e 5.apoio social. É importante que os serviços caracterizem o perfil dos usuários, sistematizem as medidas de adesão e avaliem regionalmente fatores associados à adesão, para a detecção precoce da não-adesão à TARV e estabelecimento de planos efetivos de intervenção.
Palavras-chave:
HIV; aids; Terapia Antirretroviral; adesão à medicação
Abstract:
Aids is an advanced clinical manifestation of HIV infection. It generates severe immunodeficiency and associated infections that may lead to death. The availability of antiretroviral therapy (ART) has reduced the morbidity and mortality of HIV/aids, but its benefits depend on ART adherence. This integrative review followed the PICO method to identify factors associated with ART adherence in adults. Empirical articles published between January 2010 and December 2016 in the MEDLINE, SciELO, LILACS and PePSIC databases were included. We analyzed 125 articles regarding the characteristics of the studies, adherence measurement and associated factors. The results showed great variation in the definition and measures of adherence and in the factors associated with adherence. That were categorized as follows: 1- individual variables, 2- treatment characteristics, 3- HIV/aids infection characteristics, 4- relation with the health service, 5- social support. It is important that health services characterize the profiles of users, systematize adherence measures and regionally assess factors associated with adherence, for the early detection of nonadherence to ART and implementation of effective intervention plans.
Factors associated with antiretroviral therapy adherence in adults: Integrative review.
Resumo (abstract):
Aids is an advanced clinical manifestation of HIV infection. It generates severe immunodeficiency and associated infections that may lead to death. The availability of antiretroviral therapy (ART) has reduced the morbidity and mortality of HIV/aids, but its benefits depend on ART adherence. This integrative review followed the PICO method to identify factors associated with ART adherence in adults. Empirical articles published between January 2010 and December 2016 in the MEDLINE, SciELO, LILACS and PePSIC databases were included. We analyzed 125 articles regarding the characteristics of the studies, adherence measurement and associated factors. The results showed great variation in the definition and measures of adherence and in the factors associated with adherence. That were categorized as follows: 1- individual variables, 2- treatment characteristics, 3- HIV/aids infection characteristics, 4- relation with the health service, 5- social support. It is important that health services characterize the profiles of users, systematize adherence measures and regionally assess factors associated with adherence, for the early detection of nonadherence to ART and implementation of effective intervention plans.
Carvalho, PP, Barroso, SM, Coelho, HC, Penaforte, F.R.O. Fatores associados à adesão à Terapia Antirretroviral em adultos: Revisão integrativa de literatura.. Cien Saude Colet [periódico na internet] (2017/out). [Citado em 22/12/2024].
Está disponível em: http://cienciaesaudecoletiva.com.br/artigos/fatores-associados-a-adesao-a-terapia-antirretroviral-em-adultos-revisao-integrativa-de-literatura/16471?id=16471
