0377/2017 - Fatores associados ao câncer de mama gestacional: Estudo caso-controle. Factors associated with gestational breast cancer: Case-control study.
A prevalência do câncer de mama gestacional (CMG) é 1:3.000-10.000 gestações. O objetivo é conhecer os fatores de risco (FR) associados ao CMG. Trata-se de estudo caso-controle entre janeiro de 2004 e dezembro de 2014, em maternidade de referência para gravidez de alto risco no Rio de Janeiro. Para cada um dos casos foram selecionados dois controles, totalizando 21 casos de CMG e 42 controles. Os dados foram coletados a partir de revisão de prontuários e sumários de internação e parto. Características reprodutivas, obstétricas, sociodemográficas e relativas à saúde foram investigadas. Resultados: A idade média das gestantes dos dois grupos foi 35,5 anos. A média de idade da menarca também se mostrou equivalente (12,3 anos).A idade materna na primeira gravidez foi > 30 anos em 28,6% da pacientes com CMG e em 2,4% do grupo controle (p=0,03). Utilizando regressão logística condicional pareada por idade da mãe, calcularam-se as razões de chance brutas e ajustadas e os respectivos IC95%. Os resultados apontaram que a chance de CMG aumenta 27% para cada ano a mais na idade materna na primeira gravidez (p
Palavras-chave:
Neoplasias da Mama; Gravidez
Abstract:
The prevalence of gestational breast cancer (GBC) is 1:3,000-10,000 pregnancies. The objective is to find out the risk factors associated with GBC. It’s a case-control study spanning the period between January 2004 and December 2014, at a reference maternity for high risk pregnancies, in Rio de Janeiro. For each case, two controls were recruited, in a total of 21 GBC cases and 42 controls. Data were obtained through review of medical and delivery records. Reproductive, obstetrical, sociodemographic and general health characteristics were checked. Results: The mean age of pregnant women in both groups was 35.5 years. The mean age at first period was also similar (12.3 years) in both groups. Maternal age at first pregnancy was over 30 years in 28.6% of the patients with GBC and in 2.4% of the control group (p=0.03). Crude and adjusted odds ratio and their respective CI95% were calculated through conditional logistic regression paired by maternal age.The results show the risk for GBC increases 27% for each additional year of maternal age at first pregnancy (p
Factors associated with gestational breast cancer: Case-control study.
Resumo (abstract):
The prevalence of gestational breast cancer (GBC) is 1:3,000-10,000 pregnancies. The objective is to find out the risk factors associated with GBC. It’s a case-control study spanning the period between January 2004 and December 2014, at a reference maternity for high risk pregnancies, in Rio de Janeiro. For each case, two controls were recruited, in a total of 21 GBC cases and 42 controls. Data were obtained through review of medical and delivery records. Reproductive, obstetrical, sociodemographic and general health characteristics were checked. Results: The mean age of pregnant women in both groups was 35.5 years. The mean age at first period was also similar (12.3 years) in both groups. Maternal age at first pregnancy was over 30 years in 28.6% of the patients with GBC and in 2.4% of the control group (p=0.03). Crude and adjusted odds ratio and their respective CI95% were calculated through conditional logistic regression paired by maternal age.The results show the risk for GBC increases 27% for each additional year of maternal age at first pregnancy (p
