0318/2017 - Sobrevida em 10 anos em mulheres com câncer de mama: Coorte histórica de 2000-2014. Survival in 10 years in women with breast cancer: Historiccohort 2000-2014.
Introdução: O câncer de mama é um problema de saúde pública por sua elevada incidência, morbidade e mortalidade. A análise de sobrevida dessa doença contribui para a descrição do comportamento e dos fatores prognósticos. Objetivo: Investigar a sobrevida em 10 anos após o diagnóstico, e os fatores prognósticos de mulheres com câncer de mama admitidas no Serviço de Mastologia do Sistema Único de Saúde em Joinville, Santa Catarina, entre 2000-2014. Métodos: Estudo de coorte histórica com dados dos prontuários e das declarações de óbito de 1.321 mulheres, sendo que 471 foram consideradas elegíveis nos critérios tempo de acompanhamento mínimo de 10 anos (n=288), e/ou óbito antes deste período (n=183). Análise de sobrevida realizada pelo modelo de Kaplan-Meier, Teste de Log-Rank e Regressão de Cox. Resultados:A sobrevida global em 10 anos foi 41,0% (IC95% 36,1% 45,0%). O risco de mortalidade em 10 anos estratificado pelo estadiamento tumoral foi maior entre as mulheres com invasão linfática e estadiamento II, e com 60 anos ou mais e estadiamento III.Conclusão:Os achados sugerem que a presença de invasão linfática,idade avançada eestadiamentointermediário/avançado da doença podem ser considerados indicadores de pior prognóstico para o câncer de mama.
Palavras-chave:
Neoplasias da Mama; Estadiamento de Neoplasias; Análise de Sobrevida.
Abstract:
Introduction: Breast cancer is a public health problem because of its high incidence, morbidity and mortality. Survival analysis of this disease contributes to the description of behavior and prognostic factors. Objective: To investigate survival in 10 years afterthe diagnosis and the prognostic factors of women with breast cancer admitted to the Unified Health System Mastology Service in Joinville, Santa Catarina, between 2000-2014. Methods: A historical cohort study with datathe medical records and death certificates of 1,321 womenof whom 471 were considered eligible under the minimum follow-up criteria of 10 years (n = 288), and / or death before this period (n = 183).Kaplan-Meier model, Log-Rank test and Cox regression were performed. Results: Overall survival at 10 years was41.0% (95% CI 36.1%-45.0%). The risk of 10-year mortality stratified by tumor staging was higher among women with lymphatic invasion and staging II, and blood invasion and staging IIIand at 60 years or older and staging III.Conclusion:The findings suggest that the presence of lymphatic invasion, advanced age and intermediate / advanced staging of the disease can be considered indicators of worse prognosis for breast cancer.
Keywords:
Breast Neoplasms; Staging Neoplasms; Survival analysis.
Survival in 10 years in women with breast cancer: Historiccohort 2000-2014.
Resumo (abstract):
Introduction: Breast cancer is a public health problem because of its high incidence, morbidity and mortality. Survival analysis of this disease contributes to the description of behavior and prognostic factors. Objective: To investigate survival in 10 years afterthe diagnosis and the prognostic factors of women with breast cancer admitted to the Unified Health System Mastology Service in Joinville, Santa Catarina, between 2000-2014. Methods: A historical cohort study with datathe medical records and death certificates of 1,321 womenof whom 471 were considered eligible under the minimum follow-up criteria of 10 years (n = 288), and / or death before this period (n = 183).Kaplan-Meier model, Log-Rank test and Cox regression were performed. Results: Overall survival at 10 years was41.0% (95% CI 36.1%-45.0%). The risk of 10-year mortality stratified by tumor staging was higher among women with lymphatic invasion and staging II, and blood invasion and staging IIIand at 60 years or older and staging III.Conclusion:The findings suggest that the presence of lymphatic invasion, advanced age and intermediate / advanced staging of the disease can be considered indicators of worse prognosis for breast cancer.
Palavras-chave (keywords):
Breast Neoplasms; Staging Neoplasms; Survival analysis.
Ayala, ALM, Anjos, JC, Cassol, GA, Hofelmann, D.A.. Sobrevida em 10 anos em mulheres com câncer de mama: Coorte histórica de 2000-2014.. Cien Saude Colet [periódico na internet] (2017/set). [Citado em 24/12/2024].
Está disponível em: http://cienciaesaudecoletiva.com.br/artigos/sobrevida-em-10-anos-em-mulheres-com-cancer-de-mama-coorte-historica-de-20002014/16370?id=16370&id=16370
