0241/2020 - Fatores associados à Síndrome Respiratória Aguda Grave em uma Região Central do Brasil Factors associated with Severe Acute Respiratory Infection in a Central Region of Brazil
A Síndrome Respiratória Aguda Grave (SRAG) é uma síndrome que deve ser notificada e investigada. O objetivo do estudo foi analisar o perfil epidemiológico e fatores associados à internação e óbitos por SRAG notificados em Goiás. Estudo de coorte retrospectiva, com dados das fichas de investigação do Sistema de Informação de Agravos de Notificação Influenza Web. Métodos de análise multivariada foram realizados para verificar a associação entre variáveis de exposição com os desfechos internação em UTI e óbito. Entre 2013 e 2018 foram notificados 4.832 casos de SRAG em Goiás. O principal diagnóstico etiológico foi influenza A (22,3%) com o subtipo A (H1N1pdm09) predominante, seguido pelo Vírus Sincicial Respiratório. 34,6% dos pacientes necessitaram de internação em UTI e 19% evoluíram para o óbito. Maior tempo de início do tratamento com antiviral foi associado à maior chance de internação em UTI, enquanto a não vacinação prévia contra a influenza, maior tempo para início do antiviral e idade mais avançada foram associados à maior chance de óbito. O estudo mostrou uma elevada frequência de doenças respiratórias provocadas pelo vírus Influenza no estado de Goiás e que a gravidade da síndrome, caracterizada pela internação em UTI e óbitos, está associada com o tempo de início do tratamento com o antiviral, o status vacinal e a idade do paciente.
Severe Acute Respiratory Syndrome (SARS) is a syndrome that must be reported and investigated. The objective of the study was to analyze the epidemiological profile and factors associated with hospitalization and deaths due to SARS reported in Goiás. Retrospective cohort study, with datathe investigation files of the Influenza Web Notification Diseases Information System. Multivariate analysis methods were performed to verify the association between exposure variables with the outcomes of ICU admission and death. Between 2013 and 2018, 4,832 cases of SARS were reported in Goiás. The main etiological diagnosis was Influenza A (22.3%) with the predominant subtype A (H1N1pdm09), followed by the Respiratory Syncytial Virus. 34.6% of the patients required admission to the ICU and 19% died. A longer time to start treatment with the antiviral was associated with a greater chance of admission to the ICU, while a previous non-vaccination against influenza, a longer time to start treatment and older age were associated with a higher chance of death. The study showed a high frequency of respiratory diseases caused by the Influenza virus in the state of Goiás and that the severity of the syndrome, characterized by admission to the ICU and deaths, is associated with the time of initiation of antiviral treatment with the antiviral, the vaccine status and age of the patient.
Keywords:
Human Influenza; Surveillance; Epidemiology; Severe Acute Respiratory Infection.
Factors associated with Severe Acute Respiratory Infection in a Central Region of Brazil
Resumo (abstract):
Severe Acute Respiratory Syndrome (SARS) is a syndrome that must be reported and investigated. The objective of the study was to analyze the epidemiological profile and factors associated with hospitalization and deaths due to SARS reported in Goiás. Retrospective cohort study, with datathe investigation files of the Influenza Web Notification Diseases Information System. Multivariate analysis methods were performed to verify the association between exposure variables with the outcomes of ICU admission and death. Between 2013 and 2018, 4,832 cases of SARS were reported in Goiás. The main etiological diagnosis was Influenza A (22.3%) with the predominant subtype A (H1N1pdm09), followed by the Respiratory Syncytial Virus. 34.6% of the patients required admission to the ICU and 19% died. A longer time to start treatment with the antiviral was associated with a greater chance of admission to the ICU, while a previous non-vaccination against influenza, a longer time to start treatment and older age were associated with a higher chance of death. The study showed a high frequency of respiratory diseases caused by the Influenza virus in the state of Goiás and that the severity of the syndrome, characterized by admission to the ICU and deaths, is associated with the time of initiation of antiviral treatment with the antiviral, the vaccine status and age of the patient.
Palavras-chave (keywords):
Human Influenza; Surveillance; Epidemiology; Severe Acute Respiratory Infection.
Araujo, K.L.R, Aquino, E.C, Silva, L.L.S, Ternes, Y.M.F. Fatores associados à Síndrome Respiratória Aguda Grave em uma Região Central do Brasil. Cien Saude Colet [periódico na internet] (2020/ago). [Citado em 24/12/2024].
Está disponível em: http://cienciaesaudecoletiva.com.br/artigos/fatores-associados-a-sindrome-respiratoria-aguda-grave-em-uma-regiao-central-do-brasil/17723?id=17723&id=17723
