0059/2017 - Survival rates of breast cancer and predictive factors: a hospital-based studywestern Amazon area in Brazil. Sobrevida do câncer de mama e fatores preditivos: Um estudo de base hospitalar do oeste amazônico, Brasil
• ILCE FERREIRA DA SILVA - SILVA, ILCE FERREIRA DA - Rio de Janeiro, RJ - Fundacao Oswaldo Cruz, Instituto Fernandes Figueira - <ilceferreira@yahoo.com.br>
Área Temática:
Epidemiologia
Resumo:
Na América Latina, a sobrevida em 5 anos do câncer de mama é abaixo dos países da Europa central. Não há estudos de sobrevida de câncer de mama base hospitalar no oeste da Amazônia brasileira. OBJETIVO Estimar a sobrevida hospitalar de câncer de mama e fatores associados em Rio Branco, Acre. MÉTODO Estudo de coorte de base hospitalar com todos os casos de câncer de mama diagnosticados em Rio Branco (2007-2012). As informações foram obtidas de prontuários. As sobrevidas específicas para câncer de mama foram estimadas para 1, 2, e 5 anos pelo método de Kaplan Meier. As hazards ratios (HR) brutas e ajustadas foram estimadas pela regressão proporcional de Cox. RESULTADOS A sobrevida global em 1, 2 e 5 anos foram respectivamente 95,5%, 83,7%e 87,3%. A cirurgia combinada à radioterapia afetou significativamente a sobrevida em 1, 2 e 5 anos (99%, 94% e 90,6%, respectivamente) quando comparadas a outros tratamentos (77%, 57,1% e 37,5%, respectivamente). Comparadas à cirurgia combinada, as mulheres submetidas à cirurgia isolada apresentaram maior risco de óbito, independentemente da idade e estadiamento (HR=7,23; 95%CI:2,29-22,83). CONCLUSÃO Em Rio Branco, Acre, a sobrevida em 5 anos para câncer de mama foi elevada. A cirurgia combinada à radioterapia foi independentemente associada ao menor risco de óbito.
Palavras-chave:
Sobrevida do câncer de mamaTratamentoAmazônia
Abstract:
Breast cancer survival in Latin America countries is below Central European countries. Hospital-based breast cancer survival studies in western Amazon, Brazil, are lacking. AIM. to estimate hospital-based breast cancer survival in Rio Branco, Acre, and predictor factors. METHODS Hospital-based cohort study of all women diagnosed with breast cancer (2007-2012)was proceeded. Information were obtained from medical reports, and follow-up was until 2013. One-, 2- and 5- years breast cancer specific-survival were estimated by Kaplan-Meier method. Crude and adjusted Harzards Ratios (HR) were estimated by proportional Cox regression model. RESULTS One-, 2-, and 5-year overall breast cancer survival were 95.5%, 83.7%, and 87.3% respectively. Surgery combined to radiotherapy significantly affected1-, 2-, and 5-year survival (99%, 94%, and 90.6%, respectively) as compared to other treatments (77%,57.1%, and 37.5%, respectively). Comparing to surgery combined to radiotherapy treatment, surgery alone increased the risk of death, independently of age and stage (HR=7.23;95%CI:2.29-22.83). CONCLUSIONS In Rio Branco, Acre, 5-year breast cancer survival is similar to more developed areas in Brazil. Surgery combined to radiotherapy was independently associated to a lower risk of death as compared to surgery alone and other treatment.
Sobrevida do câncer de mama e fatores preditivos: Um estudo de base hospitalar do oeste amazônico, Brasil
Resumo (abstract):
Breast cancer survival in Latin America countries is below Central European countries. Hospital-based breast cancer survival studies in western Amazon, Brazil, are lacking. AIM. to estimate hospital-based breast cancer survival in Rio Branco, Acre, and predictor factors. METHODS Hospital-based cohort study of all women diagnosed with breast cancer (2007-2012)was proceeded. Information were obtained from medical reports, and follow-up was until 2013. One-, 2- and 5- years breast cancer specific-survival were estimated by Kaplan-Meier method. Crude and adjusted Harzards Ratios (HR) were estimated by proportional Cox regression model. RESULTS One-, 2-, and 5-year overall breast cancer survival were 95.5%, 83.7%, and 87.3% respectively. Surgery combined to radiotherapy significantly affected1-, 2-, and 5-year survival (99%, 94%, and 90.6%, respectively) as compared to other treatments (77%,57.1%, and 37.5%, respectively). Comparing to surgery combined to radiotherapy treatment, surgery alone increased the risk of death, independently of age and stage (HR=7.23;95%CI:2.29-22.83). CONCLUSIONS In Rio Branco, Acre, 5-year breast cancer survival is similar to more developed areas in Brazil. Surgery combined to radiotherapy was independently associated to a lower risk of death as compared to surgery alone and other treatment.
Fujimoto, Ruth Helena Pimenta, Koifman, R. J, SILVA, ILCE FERREIRA DA. Survival rates of breast cancer and predictive factors: a hospital-based studywestern Amazon area in Brazil.. Cien Saude Colet [periódico na internet] (2017/fev). [Citado em 23/12/2024].
Está disponível em: http://cienciaesaudecoletiva.com.br/artigos/survival-rates-of-breast-cancer-and-predictive-factors-a-hospitalbased-studywestern-amazon-area-in-brazil/16105?id=16105
