0067/2024 - Vulnerabilidade à perda de seguimento e ao óbito por tuberculose nas pessoas em situação de rua no Brasil: um estudo de coorte retrospectiva Vulnerability to loss of follow-up and deathtuberculosis among homeless individuals in Brazil: a retrospective cohort study
Esta coorte retrospectiva identificou os fatores associados à perda de seguimento e ao óbito por tuberculose na população em situação de rua no Brasil, estimando-se as odds ratios (OR) e seus intervalos de confiança de 95% (IC95%) por regressão logística multinominal. Analisaram-se 3.831 casos de tuberculose nessa população, dos quais 57,0% tiveram desfechos desfavoráveis. Associaram-se à perda de seguimento: histórico de abandono (OR = 2,38; IC95% 2,05–2,77), desconhecimento da sorologia do HIV (OR = 1,79; IC95% 1,38–2,32) e coinfecção com HIV (OR = 1,73; IC95% 1,46–2,06), uso de drogas (OR = 1,54; IC95% 1,31–1,80), idade (OR = 0,98; IC95% 0,97–0,99), forma clínica mista (OR = 0,64; IC95% 0,42–0,97) e extrapulmonar (OR = 0,46; IC95% 0,29–0,73), auxílio de programa governamental (OR = 0,64; IC95% 0,50–0,81) e tratamento supervisionado (OR = 0,52; IC95% 0,45–0,60). Em relação ao óbito, associaram-se: idade (OR = 1,03; IC95% 1,01–1,05), desconhecimento da sorologia do HIV (OR = 2,39; IC95% 1,48–3,86), uso de álcool (OR = 1,81; IC95% 1,27–2,58) e tratamento supervisionado (OR = 0,70; IC95% 0,51–0,96). Percebeu-se a sobreposição de vulnerabilidades no processo saúde-doença das pessoas em situação de rua com tuberculose, demandando práticas cuidativas intersetoriais e integrais.
Palavras-chave:
Pessoas em Situação de Rua. Iniquidades em Saúde. Tuberculose. Estudos de Coortes.
Abstract:
This retrospective cohort identified factors associated with loss to follow-up and death due to tuberculosis in the homeless population in Brazil, estimating odds ratios (OR) and their 95% confidence intervals (95%CI) by multinomial logistic regression. A total of 3,831 tuberculosis cases in this population were analyzed, of which 57.0% had unfavorable outcomes. Loss to follow-up was associated with: history of abandonment (OR = 2.38; 95%CI 2.05–2.77), unknown HIV serology (OR = 1.79; 95%CI 1.38–2.32), HIV coinfection (OR = 1.73; 95%CI 1.46–2.06), drug use (OR = 1.54; 95%CI 1.31–1.80), age (OR = 0.98; 95%CI 0.97–0.99), mixed clinical form (OR = 0.64; 95%CI 0.42–0.97), extrapulmonary form (OR = 0.46; 95%CI 0.29–0.73), government program assistance (OR = 0.64; 95%CI 0.50–0.81), and supervised treatment (OR = 0.52; 95%CI 0.45–0.60). Regarding death, the following were associated: age (OR = 1.03; 95%CI 1.01–1.05), unknown HIV serology (OR = 2.39; 95%CI 1.48–3.86), alcohol use (OR = 1.81; 95%CI 1.27–2.58), and supervised treatment (OR = 0.70; 95%CI 0.51–0.96). Overlapping vulnerabilities in the health-disease process of homeless people with tuberculosis were observed, requiring comprehensive and cross-sectoral care practices.
Keywords:
Homeless people. Health Inequities. Tuberculosis. Cohort Studies.
Vulnerability to loss of follow-up and deathtuberculosis among homeless individuals in Brazil: a retrospective cohort study
Resumo (abstract):
This retrospective cohort identified factors associated with loss to follow-up and death due to tuberculosis in the homeless population in Brazil, estimating odds ratios (OR) and their 95% confidence intervals (95%CI) by multinomial logistic regression. A total of 3,831 tuberculosis cases in this population were analyzed, of which 57.0% had unfavorable outcomes. Loss to follow-up was associated with: history of abandonment (OR = 2.38; 95%CI 2.05–2.77), unknown HIV serology (OR = 1.79; 95%CI 1.38–2.32), HIV coinfection (OR = 1.73; 95%CI 1.46–2.06), drug use (OR = 1.54; 95%CI 1.31–1.80), age (OR = 0.98; 95%CI 0.97–0.99), mixed clinical form (OR = 0.64; 95%CI 0.42–0.97), extrapulmonary form (OR = 0.46; 95%CI 0.29–0.73), government program assistance (OR = 0.64; 95%CI 0.50–0.81), and supervised treatment (OR = 0.52; 95%CI 0.45–0.60). Regarding death, the following were associated: age (OR = 1.03; 95%CI 1.01–1.05), unknown HIV serology (OR = 2.39; 95%CI 1.48–3.86), alcohol use (OR = 1.81; 95%CI 1.27–2.58), and supervised treatment (OR = 0.70; 95%CI 0.51–0.96). Overlapping vulnerabilities in the health-disease process of homeless people with tuberculosis were observed, requiring comprehensive and cross-sectoral care practices.
Palavras-chave (keywords):
Homeless people. Health Inequities. Tuberculosis. Cohort Studies.
Pavinati, G., Lima, L. V., Teixeira, C. S. S., Hino, P., Bertolozzi, M.R., Nery, J. S., Magnabosco, G. T.. Vulnerabilidade à perda de seguimento e ao óbito por tuberculose nas pessoas em situação de rua no Brasil: um estudo de coorte retrospectiva. Cien Saude Colet [periódico na internet] (2024/mar). [Citado em 09/01/2025].
Está disponível em: http://cienciaesaudecoletiva.com.br/artigos/vulnerabilidade-a-perda-de-seguimento-e-ao-obito-por-tuberculose-nas-pessoas-em-situacao-de-rua-no-brasil-um-estudo-de-coorte-retrospectiva/19115?id=19115