Author:

• Leonardo Esmeraldino - Esmeraldino, L - <leoesm22@gmail.com>
ORCID: https://orcid.org/0000-0002-2910-5346

Co-author(s):

• Eliane Traebert - Traebert, E. - <elisazevedot@gmail.com>
ORCID: https://orcid.org/0000-0001-9667-7216
• Rodrigo Dias Nunes - Nunes, R. D. - <rodrigo.dias.nunes@hotmail.com>
ORCID: https://orcid.org/0000-0002-2261-8253
• Jefferson Traebert - Traebert, J. - <jefferson.traebert@gmail.com, jefferson.traebert@unisul.br>
ORCID: https://orcid.org/0000-0002-7389-985X

Abstract:

The objective was to estimate association between prenatal and neonatal factors and asthma symptoms in children at 6 years of age. A cross-sectional study using secondary data from a cohort study with a sample of 578 children was carried out. Data were analyzed using three levels hierarchical Poisson Regression. Of the 578 children included in the study, 43.4% (95% CI 39.4; 47.4) had asthma symptoms. The variables with significantly higher prevalence of symptoms and asthma at 6 years of age were: male gender, with 5% higher prevalence (PR = 1.05 95% CI 1.01; 1.11) (p = 0.043); children of pregnant women presenting infectious diseases with 7% higher prevalence (PR = 1.07; 95% CI 1.02; 1.13) (p = 0.011); children who were not breastfed, with a 12% higher prevalence (PR = 1.12; 95% CI 1.02; 1.24) (p = 0.022) and children with respiratory problems in the first month of life, with a 14% higher prevalence (PR = 1.14; 95% CI 1.01; 1.29) (p = 0.033). It could be concluded that male gender, time-independent breastfeeding deprivation and respiratory problems in the first month of life were independently associated with asthma symptoms at 6 years of age. The occurrence of infectious diseases during pregnancy was the only factor with intrauterine physiology that was associated with the occurrence of asthma symptoms at 6 years of age.

Keywords:

Asthma, Child, Child Health

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