Author:

• Alessandra Batista Marquito - Marquito, AB - <alemarkito@yahoo.com.br>
ORCID: https://orcid.org/0000-0003-0237-2521

Co-author(s):

• Hélady Sanders Pinheiro - Pinheiro, HS - <heladysanders@gmail.com>
ORCID: https://orcid.org/0000-0001-8603-1331
• Rogério Baumgratz de Paula - Paula, RB - <rogeriobaumgratz@gmail.com>
ORCID: https://orcid.org/0000-0002-7778-2907

Abstract:

Chronic kidney disease (CKD) subjects are often on polypharmacy which may expose them to drug related problems (DRP). There are no available tool in Brazil to systematically assess the
pharmacotherapy and management of PRMs in this population. This study aimed to perform a cross-cultural adaptation of PAIR criteria (Pharmacotherapy Assessment in Chronic Renal Disease) to Brazilian Portuguese. PAIR criteria consist of 50 DRP items clinically significant for CKD. The process of cross-cultural adaptation involved translation, synthesis, back-translation and an analysis by an expert committee as well as the assessment of the first draft-document. A review committee consisting of 2 pharmacists and 2 nephrologists analyzed the semantic, language, experiential and conceptual equivalence between both versions, original and translated. All items that obtained an agreement lower than 80% were reviewed. Word adjustments were made, as well as the exclusion of 6 DRP due to nonapplicability to Brazilian context. Thus, the final version of PAIR defined as “Avaliação da farmacoterapia na doença renal crônica” was translated and adapted into Brazilian Portuguese language.

Keywords:

Cross-cultural comparison. Chronic renal insufficiency. Pharmaceutical services. Patient safety.

Content:

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