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2124/2012 - Evaluation of potential drug interactions in primary health care prescriptions in Vitória da Conquista, Bahia (Brazil)
Avaliação de interações medicamentosas potenciais em prescrições da atenção primária de Vitória da Conquista-BA

Author:

• Danyllo Fábio Lessa Leão - Leão, D. F. L. - Caetité, BA - Universidade Federal da Bahia - <danyllolessa@gmail.com>

Co-author(s):

• Cristiano Soares de Moura - Moura, C. S. - Universidade Federal da Bahia - <cs_moura@yahoo.com.br>
• Danielle Souto de Medeiros - Medeiros, D. M. - Universidade Federal da Bahia - <daniellesoutomedeiros@gmail.com>
ORCID: https://orcid.org/0000-0002-2480-8990

Thematic Area:

Assistência Farmacêutica

Abstract:

Drug interactions are risk factors for adverse drug reactions occurrence. The risk for drug interactions includes factors related to prescription and intrinsic to the patient. This study aimed to evaluate the potential drug interactions in primary care prescriptions in Vitória da Conquista-BA, to fill the knowledge gap on this subject in Brazil. We collected information of several variables derived from the primary health care prescriptions. Drug interactions were evaluated from databases Medscape and Micromedex® and it was also evaluated polypharmacy frequency and its association with drug interactions occurrence. There was 48,9% frequency of drug interactions, 74,9% of moderate or greater severity, 8,6% of prescriptions in polypharmacy that in chi-square test showed positive association with drug interactions occurrence (p <0,001). Prescriptions arising from Vitória da Conquista-BA primary care showed high frequency of drug interactions, however it is necessary the analysis of other risk factors for its occurrence at this level of health care.

Keywords:

drug interactions polypharmacy primary health care quality of prescribing

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Leão, D. F. L., Moura, C. S., Medeiros, D. M.. Evaluation of potential drug interactions in primary health care prescriptions in Vitória da Conquista, Bahia (Brazil). Cien Saude Colet [periódico na internet] (2013/Jan). [Citado em 22/01/2025]. Está disponível em: http://cienciaesaudecoletiva.com.br/en/articles/evaluation-of-potential-drug-interactions-in-primary-health-care-prescriptions-in-vitoacuteria-da-conquista-bahia-brazil/12093?id=12093&id=12093



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