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0241/2020 - Factors associated with Severe Acute Respiratory Infection in a Central Region of Brazil
Fatores associados à Síndrome Respiratória Aguda Grave em uma Região Central do Brasil

Author:

• Kamilla Lelis Rodrigues de Araujo - Araujo, K.L.R - <kamillalelis@hotmail.com>
ORCID: https://orcid.org/0000-0002-0090-358X)

Co-author(s):

• Érika Carvalho de Aquino - Aquino, E.C - <erikaaquino345@gmail.com>
ORCID: https://orcid.org/0000-0002-5659-0308
• Lara Lívia Santos da Silva - Silva, L.L.S - <laraliviasantos@gmail.com>
ORCID: https://orcid.org/0000-0002-8948-7884
• Yves Mauro Fernandes Ternes - Ternes, Y.M.F - <yvesmauro@gmail.com>
ORCID: https://orcid.org/0000-0002-6240-3054


Abstract:

Severe Acute Respiratory Syndrome (SARS) is a syndrome that must be reported and investigated. The objective of the study was to analyze the epidemiological profile and factors associated with hospitalization and deaths due to SARS reported in Goiás. Retrospective cohort study, with datathe investigation files of the Influenza Web Notification Diseases Information System. Multivariate analysis methods were performed to verify the association between exposure variables with the outcomes of ICU admission and death. Between 2013 and 2018, 4,832 cases of SARS were reported in Goiás. The main etiological diagnosis was Influenza A (22.3%) with the predominant subtype A (H1N1pdm09), followed by the Respiratory Syncytial Virus. 34.6% of the patients required admission to the ICU and 19% died. A longer time to start treatment with the antiviral was associated with a greater chance of admission to the ICU, while a previous non-vaccination against influenza, a longer time to start treatment and older age were associated with a higher chance of death. The study showed a high frequency of respiratory diseases caused by the Influenza virus in the state of Goiás and that the severity of the syndrome, characterized by admission to the ICU and deaths, is associated with the time of initiation of antiviral treatment with the antiviral, the vaccine status and age of the patient.

Keywords:

Human Influenza; Surveillance; Epidemiology; Severe Acute Respiratory Infection.

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Araujo, K.L.R, Aquino, E.C, Silva, L.L.S, Ternes, Y.M.F. Factors associated with Severe Acute Respiratory Infection in a Central Region of Brazil. Cien Saude Colet [periódico na internet] (2020/Aug). [Citado em 21/01/2025]. Está disponível em: http://cienciaesaudecoletiva.com.br/en/articles/factors-associated-with-severe-acute-respiratory-infection-in-a-central-region-of-brazil/17723?id=17723



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