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0142/2023 - PRE-GESTATIONAL OVERWEIGHT AND POLYUNSATURATED FATTY ACIDS IN HUMAN MILK: THEORETICAL MODEL OF CAUSALITY
EXCESSO DE PESO PRÉ-GESTACIONAL E ÁCIDOS GRAXOS POLI-INSATURADOS NO LEITE HUMANO: MODELO TEÓRICO DE CAUSALIDADE

Author:

• Yasmin Notarbartolo di Villarosa do Amaral - Amaral, Y.N.V - <yasminamaral@hotmail.com>
ORCID: https://orcid.org/0000-0001-8159-0564

Co-author(s):

• Daniele Marano Rocha - Rocha, D. M. - <danielemarano@yahoo.com.br; daniele.araujo@iff.fiocruz.br>
ORCID: https://orcid.org/0000-0001-6985-941X
• Mariza Miranda Theme Filha - Theme-Filha M.M - <marizatheme@hotmail.com>
ORCID: https://orcid.org/0000-0002-8080-9146
• Maria Elisabeth Lopes Moreira - Moreira, M. E. L - <bebethiff@gmail.com>
ORCID: https://orcid.org/0000-0002-2034-0294


Abstract:

Introduction: Numerous studies have focused on the evaluation of the association between pre-pregnancy excess weight and polyunsaturated fatty acids in human milk. However, given the complexity of potentially confounding risk factors, the use of graphical tools is recommended to identify possible biases. Objective: To propose a theoretical model of causality using the Directed Acyclic Graph between pre-pregnancy excess weight and polyunsaturated fatty acids in human milk. Methods: An extensive literature review was performed to identify variables with causal relationships with exposure and/or outcome. The choice of variables for adjustment followed the graphic algorithm that comprises six criteria for ing a minimum set of potentially confounding variables. Results: Socioeconomic conditions, interpartum interval, maternal age and food consumption pattern were the variables that should be adjusted in order to estimate the total effect of pre-pregnancy excess weight on the content of polyunsaturated fatty acids in human milk. Conclusion: The minimum set of variables found by the present study can be used in the analysis of other studies that evaluate this association.

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Amaral, Y.N.V, Rocha, D. M., Theme-Filha M.M, Moreira, M. E. L. PRE-GESTATIONAL OVERWEIGHT AND POLYUNSATURATED FATTY ACIDS IN HUMAN MILK: THEORETICAL MODEL OF CAUSALITY. Cien Saude Colet [periódico na internet] (2023/Jun). [Citado em 27/12/2024]. Está disponível em: http://cienciaesaudecoletiva.com.br/en/articles/pregestational-overweight-and-polyunsaturated-fatty-acids-in-human-milk-theoretical-model-of-causality/18768?id=18768



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