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0089/2020 - Prevalência da artrite reumatoide na America do Sul: Revisão sistemática e meta-analise
Prevalence of rheumatoid arthritis in South-America: A systematic review and meta-analysis

Author:

• Jaqueline L. Germano - Germano, J.L - <jaque_lg@hotmail.com>
ORCID: https://orcid.org/0000-0003-4813-0675

Co-author(s):

• Joana Reis-Pardal - Reis-Pardal, J - <joanareisp@gmail.com>
ORCID: https://orcid.org/0000-0002-0314-8233
• Fernanda S. Tonin - Tonin, F.S - <stumpf.tonin@ufpr.br>
ORCID: https://orcid.org/0000-0003-4262-8608
• Roberto Pontarolo - Pontarolo, R. - <pontarolo@ufpr.br>
ORCID: https://orcid.org/0000-0002-7049-4363
• Ana Carolina Melchiors - Melchiors, A.M. - <anamelchiors@ceunes.ufes.br>
ORCID: https://orcid.org/0000-0002-8538-2903
• Fernando Fernandez-Llimos - Fernandez-Llimos, F - <fllimos@ff.up.pt>
ORCID: https://orcid.org/0000-0002-8529-9595


Abstract:

Rheumatoid arthritis (RA) is among the most prevalent chronic autoimmune and inflammatory diseases worldwide. Estimates of prevalence vary among regions and sources of information. Thus, the aim of this study was to establish a pooled estimate of the RA prevalence in South America by means of a meta-analysis of the available epidemiologic studies. Systematic searches in Pubmed, Lilacs, Scielo, Scopus, and Web of Science databases (updated May 2019) were done followed by a systematic grey literature search to identify original research articles and reports, published after 2000, providing data of RA prevalence in any South American country. Proportion meta-analysis of weighted pooled (prevalence of RA) was performed, with between-trial heterogeneity assessed by the inconsistency relative index. Sensitivity analyses and sub-group analyses were also done. A total of 24 articles, representing 27 population-based studies were included. Pooled prevalence of RA resulted in 0.48% [95% CI 0.38%-0.62%] (I2=90%) with 591.981 cases in a population of 114.537.812 individuals (I2 = 99%). Brazil and Colombia presented the lowest rates of RA prevalence (0.22% [0.05%-0.91%], and 0.24% [0.15%-0.39%], respectively. RA prevalence in indigenous population was higher (1.45% [0.88%-2.37%]), and studies using COPCORD method reported also the highest rates (1.07% [0.74%-1.55%]).

Keywords:

Arthritis, Rheumatoid ; Prevalence ; Latin America ; Health Services Accessibility • Meta-Analysis as Topic

Content:

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Germano, J.L, Reis-Pardal, J, Tonin, F.S, Pontarolo, R., Melchiors, A.M., Fernandez-Llimos, F. Prevalência da artrite reumatoide na America do Sul: Revisão sistemática e meta-analise. Cien Saude Colet [periódico na internet] (2020/May). [Citado em 27/09/2024]. Está disponível em: http://cienciaesaudecoletiva.com.br/en/articles/prevalencia-da-artrite-reumatoide-na-america-do-sul-revisao-sistematica-e-metaanalise/17571



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