Author:

• Pedro Curi Hallal - Hallal, P.C - <prchallal@gmail.com>
ORCID: https://orcid.org/0000-0003-1470-6461

Co-author(s):

• Fernando C. Barros - Barros, F. C. - <fcbarros.epi@gmail.com>
ORCID: https://orcid.org/0000-0001-5973-1746
• Mariângela Freitas Silveira - Silveira, M. F. - <mariangelafreitassilveira@gmail.com>
ORCID: https://orcid.org/0000-0002-2861-7139
• Aluísio J D Barros - Barros, A.J.D - <abarros.epi@gmail.com>
ORCID: https://orcid.org/0000-0002-2022-8729
• Odir A Dellagostin - Dellagostin, OA - <odirad@gmail.com>
ORCID: https://orcid.org/0000-0003-2803-4088
• Lúcia C Pellanda - Pellanda, Lúcia C - <lupellanda@gmail.com>
ORCID: https://orcid.org/0000-0002-8776-2248
• Cláudio José Struchiner - Struchiner, C. J. - <claustru@gmail.com>
ORCID: https://orcid.org/0000-0003-2114-847X
• Marcelo N Burattini - Burattini, M.N - <mnburatt@gmail.com>
ORCID: https://orcid.org/0000-0002-5407-6890
• Fernando P Hartwig - Hartwig, FP - <fernandophartwig@gmail.com>
ORCID: https://orcid.org/0000-0003-3729-0710
• Ana Maria Baptista Menezes - Menezes, A.M.B - <anamene.epi@gmail.com>
ORCID: https://orcid.org/0000-0002-4129-0898
• Bernardo L Horta - Horta, BL - <blhorta@gmail.com>
ORCID: https://orcid.org/0000-0001-9843-412X
• Cesar Gomes Victora - Victora, C. G. - <cvictora@gmail.com>
ORCID: https://orcid.org/0000-0002-2465-2180

Abstract:

The first case of COVID-19 was reported in China in December 2019, and, as the virus
has spread worldwide, the World Health Organization declared it a pandemic. Estimates on the number of COVID-19 cases do not reflect it real magnitude as testing is limited. Population based data on the proportion of the population with antibodies is relevant for planning public health policies. We aim to assess the prevalence of SARS-CoV-2 antibodies, presence of signs and symptoms of COVID-19, and adherence to isolation measures. A random sample comprising 133 sentinel citiesall states of the country will be ed. Three serological surveys, two weeks apart, will be conducted. The most populous municipality in each intermediate region of the country, defined by the Brazilian Institute of Geography and Statistics, was chosen as sentinel city. In each city,25 census tracts will be ed, and 10 households will be systematically sampled in each tract, totaling 33,250 participants. In each household, one inhabitant will be randomly ed to be interviewed and tested for antibodies against SARS-CoV-2, using WONDFO SARS-CoV-2 Antibody Test. By evaluating a representative sample of Brazilian sentinel sites, this study will provide essential information for the design of health policies.

Keywords:

COVID19, epidemiology, serological survey.

Content:

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