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0094/2017 - Tratamento antirrábico humano pós-exposição em relação à situação epidemiológica da doença
Human rabies post-exposure prophylaxis relative to the disease epidemiological status

Author:

• Bruno Fonseca Martins da Costa Andrade - Andrade, Bruno Fonseca Martins da Costa - Hospital UNIMED Araçatuba - <bfmca@hotmail.com>

Co-author(s):

• Taísa Santos de Melo Andrade - Andrade, Taísa Santos de Melo - Santa Casa de Misericórdia de Araçatuba, - <taisasmelo@hotmail.com>
• Luzia Helena Queiroz - Queiroz, Luzia Helena - niversidade Estadual Paulista Julio de Mesquita Filho - <luziahqueiroz@gmail.com>

Thematic Area:

Epidemiologia

Abstract:

This study evaluated the prophylactic measures adopted after attacks by dogs and cats in the main city of Northwester São Paulo State, based on the technical manual for post-exposure treatment, considering the not controlled (1990-1996) and controlled (1997-2010) rabies status. A retrospective analysis was done using the data from the SINAN records (W64-CID10) between 1990 and 2010. In most cases, the accidents were mild (76.9%), and biting animals were healthy (75.4%); therefore, no treatment was needed in 53.3% of the cases. In 64.6% of cases, the prescribed PEP treatment was inappropriate. The most indicated PEP treatments consisted of vaccine and RIG (43.4%), and either three doses of mouse brain vaccine or two doses of cell culture vaccine (76.5%), during the not controlled and controlled rabies periods, respectively. The treatment was more appropriate and followed the technical recommendations during controlled rabies periods compared to not controlled (p<0.0001) periods. However, excessive application of RIG and rabies vaccine was observed in both periods.

Keywords:

Rabiesanimal aggressionPost-exposure prophylaxisImmunization scheduleDogs

Content:

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Cite

Andrade, Bruno Fonseca Martins da Costa, Andrade, Taísa Santos de Melo, Queiroz, Luzia Helena . Tratamento antirrábico humano pós-exposição em relação à situação epidemiológica da doença. Cien Saude Colet [periódico na internet] (2017/Mar). [Citado em 15/04/2025]. Está disponível em: http://cienciaesaudecoletiva.com.br/en/articles/tratamento-antirrabico-humano-posexposicao-em-relacao-a-situacao-epidemiologica-da-doenca/16140



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