0159/2018 - The sensitivity, specificity, and agreement of a point of care method: an assessment of the diagnostic accuracy. Sensibilidade, especificidade e concordância do método point of care: um estudo de precisão diagnóstica.
O uso de novas tecnologias pode melhorar o screening em comunidades de difícil acesso à saúde. Objetivo: Avaliar a sensibilidade, especificidade e concordância do teste de point of care em comparação com método laboratorial para dosagem de Glicose (GLI), Triglicerídeo (TG) e Colesterol total (CT). Método: Estudo prospectivo com dados de população de adultos remanescentes de quilombolas no Brasil. Exames laboratoriais convencionais para análise foram obtidos por venopunção, utilizados como método padrão para mensuração das concentrações de GLI (mg/dL), TG (mg/dL) e CT (mg/dL) e comparados a mensuração por meio de técnica de ponta de dedo (point of care). Tabelas de contingência (2x2) foram utilizadas para estimar sensibilidade e especificidade dos métodos e o coeficiente de Lin e análises de Bland & Altman foram métodos de concordância com nível de significância de 5%. Resultados: Houve concordância substancial entre os métodos para mensuração de TG e fraca concordância para mensuração de CT e GLI. Os coeficientes de Bland & Altman indicam que o método de ponta de dedo não apresentou boa mensuração. Conclusão: O método point of care não apresentou boa capacidade de mensuração de Glicose, Triglicerídeo e Colesterol total tendo como referência o método laboratorial.
Palavras-chave:
Point of care Systems, Testes Laboratoriais, Avaliação da tecnologia biomédica.
Abstract:
The use of new technologies can improve screening in communities with difficult access to health. Objective: To evaluate the sensitivity, specificity, and agreement of a point of care test in comparison to laboratory methods for the determination of glucose (GLI), triglyceride (TG), and total cholesterol (TC) concentrations. Methods: This prospective study used datathe remaining adult population of a quilombolas in Brazil. Laboratory tests using conventional methods for the analysis of venipuncture samples were used as a standard method to measure the concentrations of GLI (mg/dL), TG (mg/dL), and TC (mg/dL) and compared to the metered dosethe collection of fingertip capillary blood (point of care). Contingency tables (2x2) were used to estimate the sensitivity and specificity of the methods. Lin and Bland & Altman coefficients were used to statistically assess agreement, the level of significance was 5%. Results: There was substantial agreement between the methods for measuring TG and poor agreement for of TC and GLI. Analysis of the Bland & Altman coefficients revealed that the fingertip method did not produce good measures. Conclusion: The point of care method did not offer a good ability to measure compared to that of the reference laboratory method.
Keywords:
Point of care, Laboratory tests. Technology Assessment.
Sensibilidade, especificidade e concordância do método point of care: um estudo de precisão diagnóstica.
Resumo (abstract):
The use of new technologies can improve screening in communities with difficult access to health. Objective: To evaluate the sensitivity, specificity, and agreement of a point of care test in comparison to laboratory methods for the determination of glucose (GLI), triglyceride (TG), and total cholesterol (TC) concentrations. Methods: This prospective study used datathe remaining adult population of a quilombolas in Brazil. Laboratory tests using conventional methods for the analysis of venipuncture samples were used as a standard method to measure the concentrations of GLI (mg/dL), TG (mg/dL), and TC (mg/dL) and compared to the metered dosethe collection of fingertip capillary blood (point of care). Contingency tables (2x2) were used to estimate the sensitivity and specificity of the methods. Lin and Bland & Altman coefficients were used to statistically assess agreement, the level of significance was 5%. Results: There was substantial agreement between the methods for measuring TG and poor agreement for of TC and GLI. Analysis of the Bland & Altman coefficients revealed that the fingertip method did not produce good measures. Conclusion: The point of care method did not offer a good ability to measure compared to that of the reference laboratory method.
Palavras-chave (keywords):
Point of care, Laboratory tests. Technology Assessment.
Maciel, ES, Quaresma, F, Figueiredo, FWS, Sarraf, JS, Luis, TP, Sesti, LFC, Fonseca, FLA, Adami, F. The sensitivity, specificity, and agreement of a point of care method: an assessment of the diagnostic accuracy.. Cien Saude Colet [periódico na internet] (2018/abr). [Citado em 22/12/2024].
Está disponível em: http://cienciaesaudecoletiva.com.br/artigos/the-sensitivity-specificity-and-agreement-of-a-point-of-care-method-an-assessment-of-the-diagnostic-accuracy/16692?id=16692&id=16692
